Sustain Release Formulation and Evaluation of Ofloxacin Floating Delivery System
نویسندگان
چکیده
منابع مشابه
Formulation and in vitro evaluation of ofloxacin as floating drug delivery system
The present study outlines a systematic approach for designing and development of Ofloxacin floating tablets to enhance the bioavailability and therapeutic efficacy of the drug. Floating tablets of Ofloxacin have shown controlled release thereby proper duration of action at a particular site and are designed to prolong the gastric residence time after oral administration. Floating tablets of Of...
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A multiple unit oral floating drug delivery system of famotidine was developed to prolong gastric residence time, target stomach mucosa and increase drug bioavailability. Drug and polymer compatibility was studied by subjecting physical mixtures of drug and polymers to differential scanning calorimetry. Cod liver oil entrapped calcium alginate beads containing famotidine, capable of floating in...
متن کاملFormulation of Gastroretentive floating microparticles for Ofloxacin
In the present study an attempt was made to prepare alginate floating microparticles by ionotropic gelation method with calcium carbonate (CaCO3) 1% w/v in gelation medium used as gas-forming agent for oral delivery of Ofloxacin. Chitosan was used to enhance the drug encapsulation efficiency. Various physiochemical properties such as particle size, shape, in vitro buoyancy and drug release was ...
متن کاملFormulation Development and Evaluation of Gastro Retentive Floating Drug Delivery System for Novel Fluoroquinolone using Natural and Semisynthetic Polymers
The purpose of present research work is to develop gastro retentive formulation for Moxifloxacin using various release retardants. Moxifloxacin, novel synthetic fluoro quinolone, antibacterial agent. Floating tablets of Moxifloxacin. HCl were prepared using variable amounts of HPMCK4M, HPMCK15M and HPMCK100M with effervescent mixtures by direct compression technique. Totally 9 formulations were...
متن کاملOfloxacin Ocular Inserts: Design, Formulation and Evaluation
In developing a drug delivery strategy, issues of absorption, distribution, metabolism, and elimination must be considered. The eye presents unique opportunities and challenges when it comes to the delivery of pharmaceuticals. While absorption by this route is bungling, there are few side effects with conventional ocular dosage forms. Hence, ocular inserts were prepared with prolonged release o...
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ژورنال
عنوان ژورنال: International Letters of Chemistry, Physics and Astronomy
سال: 2014
ISSN: 2299-3843
DOI: 10.18052/www.scipress.com/ilcpa.31.69